Unexplained infertility

Some couples are infertile, and it is not possible to explain the exact cause of their infertility. We call it unexplained infertility.

At unexplained infertility all examinations of the man and the woman show that their reproductive system is normal. Of course, this does not mean that there is no a cause of their infertility, but merely that we presently cannot tell the cause of their infertility. We experience unexplained infertility in approx. 10-15% of the couples we treat.

Before we diagnose a couple as unexplained infertile, it is important that we relate to the period of time the couple has been infertile and to the age of the woman. Women over 35 years of age are recommended active fertility treatment after having actively tried to become pregnant for 6 months. Fertility is reduced concurrently with the age of the women, especially after she has passed 35 years of age.


Even though we do not know the exact cause of infertility, we have good experience with treating infertility.

Usually we give the woman a mild form of hormone treatment to stimulate the process of maturing the eggs, after that we inseminate the man’s sperm cells into the woman’s uterus when she has ovulation. This form of treatment is called IUI. If the insemination is not successful, we proceed to in vitro fertilisation, called IVF.

Treatment with hormones assists the egg in its phase of maturation, whereas the insemination secures that the sperm cells are added to the egg exactly at the time of the ovulation. This can be an advantage, as we assume that unexplained infertility is caused by:

  • The woman’s eggs have troubles disengaging from the ovaries
  • The sperm cells do not survive very long in the uterine tubes
  • The woman might produce an antidote, which kills the sperm cells on their way to the uterus

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Existing research results prove that with the above treatments we achieve the same or probably better results than we do with other forms of treatment for known causes of infertility. Thus, approx. 60-70% of the couples we treat for unexplained infertility become pregnant and give birth to a child.

The treatment is effective, as we assume that unexplained infertility is caused by relatively uncomplicated conditions in the reproductive system and is therefore in many cases fairly simple to treat.



Progress with PGD for Sickle Cell prevention
Studies in Denmark and Belgium.

Good IVF success rates after single embryo transfers
Transferring one IVF embryo, followed by a second, is almost as likely to result in a pregnancy as transferring two at a time.

IUI workshop
At University of Maiduguri Teaching Hospital

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